List of Analgesics

Analgesics, also known as "painkillers" or "pain relievers", are medications that provide temporary pain relief - they do not treat the cause of the pain.

Listing of generic (chemical) and corresponding brand names of analgesics classified by types.

Non-Narcotic Analgesics

Acetaminophen is not classified as an NSAID because it only exerts weak anti-inflammatory effects.

Generic name Brand names
Acetaminophen (Paracetamol) Tylenol, Acephen, Actamin, Apacet, Genapap, Feverall, Halenol, Panadol, Panex, Paramol, Pediapap, Redutemp, Q-Pap, Tactinal, Tempra, Tylophen, Uniserts
Metamizole (Dipyrone) (banned in US, Japan, Australia) Novalgin, Analgin, Berlosin, Dipirona, Metalgin, Metamizol-Puren, Novaminsulfon


Non-Steroidal AntiIinflammatory Drugs (NSAIDs) reduce pain and inflammation by reducing the production of prostaglandins (pro-inflammatory chemicals) through inhibition of the enzyme cyclooxygenase (COX). Prostaglandins are released by the damaged tissue, that is at the source of the pain, therefore NSAIDs are classified as peripherally acting analgesics 1. They have no effect on the perception of pain.

List of NSAIDs:

Generic name Brand name
Aspirin (acetylsalicylic acid) Acuprin, Anacin, Aspidrox, Aspir-Mox, Aspirtab, Bufferin, Easprin, Ecotrin, Entaprin, Genprin, Halfprin, Magnaprin, Miniprin, Ridiprin, Sloprin, Uni-Buff, Zorprin
Diclofenac Voltaren, Cataflam, Zipsor
Dexibuprofen Seractil
Diflunisal Dolobid
Etodolac Lodine, Eccoxolac, Etopan
Fenoprofen Nalfon
Flufenamic acid Mobilat, Flufen, Fenazol
Flurbiprofen Ansaid
Ibuprofen Motrin, Advil, Brufen, Ibulgan, Fenbid, Midol IB, Nuprin, Nurofen, Rufen
Indomethacin Indocin
Ketoprofen Orudis, Oruvail, Actron, Ketoflam, Ketonal
Ketorolac Toradol, Sprix, Etorac
Lornoxicam Xefo
Loxoprofen Loxonin
Meclofenamic acid Meclofenamate Sodium
Mefenamic acid Ponstel
Meloxicam Mobic
Nabumetone Relafen
Naproxen Naprosyn, Aleve, Anaprox, Naprelan
Oxaprozin Daypro
Piroxicam Feldene, Roxam
Salsalate Disalcid, Anaflex, Amigesic, Salflex
Sulindac Clinoril
Tenoxicam Mobiflex, Tilcotil, Tobitil
Tolmetin Tolectin
Tolfenamic acid Clotam

COX-2 Inhibitors (Coxibs)

The selective COX-2 inhibitors do not interfere with COX-1. COX-1 enzyme is normally present in most body tissues, and plays an inportant role in the functioning of the gastrointestinal tract, kidneys and platelets. In contrast, COX-2 is produced primarily in response to inflammation, but to some extent in other tissues including kidneys and brain.

Generic name Brand names
Celecoxib Celebrex
Rofecoxib (withdrawn from market) Vioxx
Valdecoxib (withdrawn from market) Bextra
Parecoxib (withdrawn in US, licenced in EU) Dynastat
Etoricoxib (withdrawn in US, licenced in EU) Arcoxia

Opioid Analgesics (Painkillers)

Opioid analgesics, also known as narcotic analgesics, relieve pain by acting on various receptors in the central nervous system (brain and spinal cord).

Generic name Brand names
Buprenorphine Subutex
Butorphanol Stadol
Codeine see Combination analgesics
Hydrocodone see Combination analgesics
Hydromorphone Dilaudid
Levorphanol Levo-Dromoran
Meperidine Demerol, Meperitab
Methadone Dolophine, Methadone Diskets, Methadose
Morphine MS Contin, Kadian, Roxanol
Nalbuphine Nubain
Oxycodone OxyContin, Roxicodone, OxyIR, Oxyfast
Oxymorphone Opana, Numorphan
Pentazocine Talwin
Propoxyphene Darvon, Darvon-N

Note: Naloxone (Narcan), an pioid antagonist, is used for reversal of opioid effects in acute overdose.

Centrally Acting Analgesics

These analgesics work as mu-opioid-receptor agonists and monoamine-reuptake inhibitors 2.

Generic name Brand names
Tapentadol Nucynta, Palexia
Tramadol Ultram

Combination Analgesics

The combination analgesic contains either one or more types of analgesics with other medications in a single tablet. A combination is most effective when its components work through different analgesic mechanisms and synergistically.

Here are listed combination medications:

Generic name Brand names
Acetaminophen, Aspirin Excedrin Back & Body
Acetaminophen, Aspirin, Caffeine Excedrin, Genace, Supac, Vanquish
Acetaminophen, Aspirin, Caffeine, Salicylamide Levacet, Saleto
Acetaminophen, Caffeine, Magnesium Salicylate Backprin, Durabac Forte
Acetaminophen, Caffeine, Phenyltoloxamine, Salicylamide Cafgesic, Combiflex, Durabac
Acetaminophen, Caffeine, Isometheptene Migralam, MigraTen, Prodrin
Acetaminophen, Butalbital Bupap, Cephadyn, Marten-Tab, Phrenilin, Promacet, Sedapap
Acetaminophen, Salicylamide Panritis Forte
Acetaminophen, Caffeine Excedrin Tension Headache, Excedrin Quick Tab, Valorin Extra
Acetaminophen, Phenyltoloxamine Dologesic, Flextra-650, Novagesic, Rhinoflex, Staflex
Aspirin, Caffeine Anacin, P-A-C
Aspirin, Caffeine, Salicylamide B C Powder, Emagrin, Stanback Fast Pain Relief
Aspirin, Caffeine, Orphenadrine Norgesic, Orphengesic
Aspirin, Meprobamate Equagesic, Micrainin
Butalbital, Acetaminophen, Caffeine Alagesic, Dolgic Plus, Esgic, Fioricet, Geone, Margesic, Medigesic, Repan, Zebutal
Butalbital, Aspirin, Caffeine Fiorinal, Fiormor, Fiortal, Fortabs, Idenal, Laniroif
Butalbital, Acetaminophen, Caffeine, Codeine Fioricet with Codeine
Butalbital, Aspirin, Caffeine, Codeine Fiorinal with Codeine, Idenal with Codeine
Buprenorphine, Naloxone Suboxone
Codeine, Acetaminophen Cocet, Cocet Plus, Tylenol with Codeine #3, Vopac
Codeine, Aspirin Aspalgin
Codeine, Ibuprofen Nurofen Plus, Ardinex
Codeine, Acetaminophen, Doxylamine Mersyndol, Panalgesic
Dihydrocodeine, Acetaminophen, Caffeine Trezix, Panlor
Dihydrocodeine, Aspirin, Caffeine Synalgos-DC
Hydrocodone, Acetaminophen Anexia, Dolacet, Lorcet, Lortab, Maxidone, Norco, Reprexain, Vicodin, Zydone
Hydrocodone, Aspirin Damason-P, Azdone, Panasal 5/500, Lortab ASA
Hydrocodone, Ibuprofen Vicoprofen, Reprexain, Ibudone
Oxycodone, Acetaminophen Endocet, Narvox, Magnacet, Percocet, Roxicet, Tylox,
Oxycodone, Aspirin Endodan, Percodan, Roxiprin
Oxycodone, Ibuprofen Combunox
Propoxyphene, Acetaminophen Balacet, Darvocet, Propacet 100, Wygesic
Propoxyphene, Aspirin Bexophene
Propoxyphene, Aspirin, Caffeine Darvon Compound, PC-CAP
Pentazocine, Acetaminophen Talacen
Pentazocine, Aspirin Talwin Compound
Tramadol, Acetaminophen Ultracet


  • 1. Urquhart E. Semin Arthritis Rheum. 1993 Dec;23(3):198-205.
  • 2. Guay DR. Consult Pharm. 2009 Nov;24(11):833-40.

Author: OriginalDrugs Team
Last reviewed: April 21, 2013

Interesting facts

  • Paracetamol, a para-aminophenol derivative, is not a NSAID but is commonly discussed in the same arena as aspirin and NSAIDs.
  • Paracetamol has no (or very little) anti-inflammatory and anti-platelet effects because it mainly acts centrally but these are peripheral actions.
  • Traditional NSAIDs are non-selective and inhibit both COX-1 and COX-2 enzymes.