Fluoxetine HCl (Prozac)
What is Fluoxetine used for?
Fluoxetine and Depression
Fluoxetine has a slower onset of antidepressant effect than other antidepressants. So, in situations such as in severe depression, when the fast therapeutic effect is particularly important, fluoxetine may be inappropriate.
Fluoxetine is activating, so it is a good choice for depressed patients with hypersomnia or psychomotor retardation.
Depression in children and adolescents
Fluoxetine is the only antidepressant with FDA-approved labeling for the treatment of depression in children (over 8 years of age) and teenagers. Research shows fluoxetine combined with cognitive behaviour therapy works well for teenagers with moderate or severe depression2.
There is a small risk that children taking fluoxetine might hurt themselves. Self-harm thoughts are less likely to happen if they have a counseling treatment at the same time.
Fluoxetine (Prozac) dosage for depression:
Adults: Initially, 20 mg/day (in the morning). Wait a few weeks and, if needed, the dose may be gradually increased up to a maximum of 80 mg/day.
Children 8 years and older: Initially, 10 mg or 20 mg daily. Children starting at 10 mg may have their dose increased to 20 mg a day after 1 week. Underweight children may remain at the 10 mg daily.
When is the best time of day to take fluoxetine?
The best time to take fluoxetine (Prozac) is in the morning, because it is activating.
Last updated: February, 2015
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